Mild metal-free sequential dual oxidative amination of C(sp~3)-H bonds: Efficient synthesis of imidazo[1,5-a]pyridines

摘要

A metal-free sequential dual oxidative amination of C(sp~3)-H bonds under ambient conditions was the first developed, affording imidazo[1,5-a]pyridines in good to excellent yields. The reaction was involved in two oxidative C-N couplings and one oxidative dehydrogenation process with six hydrogen atoms removed.