Cipadonoid A, a novel limonoid with an unprecedented skeleton, from Cipadessa cinerasecns

摘要

Cipadonoid A (1), a novel limonoid with an unprecedented skeleton, was isolated from the leaves of Cipadessa cinerasecns. its structure and relative configuration were determined by spectroscopic analysis and computer modeling. 1 represents a new type of limonoid, characterized by a rearranged tetrahydropyranyl ring B incorporating usually exocyclic C-30. A possible biosynthetic pathway of 1 was also proposed.