Hepatocellular Carcinoma: Stiffness Value and Ratio to Discriminate Malignant from Benign Focal Liver Lesions

Lu Qiang; Ling Wenwu; Lu Changli; Li Jiawu; Ma Lin; Quan Jierong; He Du; Liu Jianping; Yang Jiaying; Wen Tianfu; Wu Hong; Zhu Hongguang; Luo Yan

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Hepatocellular Carcinoma: Stiffness Value and Ratio to Discriminate Malignant from Benign Focal Liver Lesions

机译：肝细胞癌：刚度值和区分良性局灶性肝病变恶性肿瘤的比率

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Purpose: To investigate the use of stiffness value and stiffness ratio (ratio of lesion to background liver parenchyma values) to discriminate malignant from benign focal liver lesions by using histologic results as the reference standard.

机译：目的：研究以组织学结果为参考标准，使用刚度值和刚度比（病变与背景肝实质值之比）来区分恶性与良性局灶性肝病变。

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《Radiology》 |2015年第3期|共9页
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Lu Qiang; Ling Wenwu; Lu Changli; Li Jiawu; Ma Lin; Quan Jierong; He Du; Liu Jianping; Yang Jiaying; Wen Tianfu; Wu Hong; Zhu Hongguang; Luo Yan;
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专利

1. Hepatocellular Carcinoma: Stiffness Value and Ratio to Discriminate Malignant from Benign Focal Liver Lesions [J] . Lu Qiang, Ling Wenwu, Lu Changli, Radiology . 2015,第3期

机译：肝细胞癌：刚度值和区分良性局灶性肝病变恶性肿瘤的比率
2. CONTRAST ENHANCED SONOGRAPHIC ASSESSMENT OF FEEDING VESSELS AS A DISCRIMINATOR BETWEEN MALIGNANT VS. BENIGN FOCAL SPLENIC LESIONS [J] . Taeymans Olivier, Penninck Dominique . Veterinary Radiology & Ultrasound . 2011,第4期

机译：输卵管造影剂超声造影评估作为恶性诉与诉之间的判别器。良性局部脾脏病变
3. Utility of glypican-3 and survivin in differentiating hepatocellular carcinoma from benign and preneoplastic hepatic lesions and metastatic carcinomas in liver fine-needle aspiration biopsies. [J] . Nassar A, Cohen C, Siddiqui MT Diagnostic cytopathology . 2009,第9期

机译：glypican-3和survivin在区分肝细针穿刺活检中的肝细胞癌与良性和癌前肝损害以及转移性癌中的作用。
4. Benign and Malignant Diagnosis of Hepatocellular Carcinoma on CT Images Based on Fusion Network [C] . Qinyu Wang, Chunhua Deng, Shiwen Zhang, Chinese Automation Congress . 2019

机译：基于融合网络的CT图像对肝细胞癌的良恶性诊断
5. Differentiating benign and malignant inflammatory breast lesions: Value of T2 weighted and diffusion weighted MR images [D] . Kanao, Shotaro 2019

机译：区分乳腺良性和恶性炎症病变：T2加权和弥散加权MR图像的价值
6. Evaluation of ADCratio on liver MRI diffusion to discriminate benign versus malignant solid liver lesions [O] . Tarun Pankaj Jain, Wen Ter Kan, Sean Edward, 2018

机译：评价肝脏核磁共振弥散以鉴别良性和恶性实体肝病变的ADC比值
7. Aim: To investigate the value of ElastPQ measurement for differential diagnosis of benign and malignant focal liver lesions (FLLs) by using histologic results as a reference standard. Material and methods: A total of 154 patients were included. ElastPQ measurement was performed for each lesion in which the shear wave speed (SWS) was measured. The difference in SWS and SWS ratio of FLL to surrounding liver were evaluated, and the cut off value was investigated. Receiver operating characteristic (ROC) curve was plotted to evaluate the diagnostic performance. Histology as a gold standard was obtained by surgery in all patients. Results: A total of 154 lesions including 129 (83.7 ) malignant FLLs and 25 (16.3 ) benign ones were analysed. The SWS of malignant and benign FLLs was significantly different, 2.77±0.68 m/s and 1.57±0.55 m/s (p<0.05). The SWS ratio of each FLL to surrounding liver parenchyma was 2.23±0.49 for malignant and 1.14±0.36 for benign FLLs (p<0.05). The cut off value for differential diagnosis was 2.06 m/s for SWS and 1.67 for SWS ratio. Conclusions: ElastPQ measurement provides reliable quantitative stiffness information of FLLs and may be helpful in the differential diagnosis between malignant and benign FLLs. [O] . Yi Dong, Wen-Ping Wang, Yadan Xu, 2017

机译：目的：通过使用组织学结果作为参考标准，研究ELASTPQ测量对良性和恶性局灶性肝病变（FLLS）的鉴别诊断的价值。材料和方法：共有154名患者。对测量剪切波速度（SWS）的每个病变进行ELASTPQ测量。评估了FL1与周围肝脏的SWS和SWS比的差异，研究了切断值。接收器操作特征（ROC）曲线被绘制以评估诊断性能。组织学作为金标准通过患者的手术获得。结果：共有154例病变，包括129名（83.7％）恶性FLLS和25（16.3％）良性物质。 SWS的恶性和良性FLLS显着差异，2.77±0.68 m / s和1.57±0.55 m / s（p <0.05）。对于良性FLL的恶性为2.23±0.36，每个FL1与周围肝实质的SWS比为2.23±0.36（P <0.05）。差分诊断的切断值为SWS和SWS比率为2.06米/秒。结论：ELASTPQ测量提供了FLLS的可靠定量刚度信息，可能有助于恶性和良性FLL之间的差异诊断。

Hepatocellular Carcinoma: Stiffness Value and Ratio to Discriminate Malignant from Benign Focal Liver Lesions

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