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首页> 外文期刊>Nucleic Acids Research >Full-Malaria/Parasites and Full-Arthropods: databases of full-length cDNAs of parasites and arthropods, update 2009.
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Full-Malaria/Parasites and Full-Arthropods: databases of full-length cDNAs of parasites and arthropods, update 2009.

机译:全疟疾/寄生虫和全节肢动物:寄生虫和节肢动物全长cDNA数据库,2009年更新。

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摘要

Full-Malaria/Parasites is a database for transcriptome studies of apicomplexa and other parasites, which is based on our original full-length cDNA sequences and physical cDNA clone resources. In this update, the database has been expanded to contain the shogun sequencing for the entire sequences of 14 818 non-redundant full-length cDNA clones from six apicomplexa parasites and 6.8 million of transcription start sites (TSS), both of which had been produced by novel protocols using the oligo-capping method and the Illumina GA sequencer. The former should be the ultimate data for exact annotation of the expressed genes, while the latter should be useful for ultra-deep expression analysis. Furthermore, we have launched Full-Arthropods, a full-length cDNA database for arthropods of medical importance. Full-Arthropods contains 50 343 one-pass sequences, 10 399 shotgun complete sequences and 22.4 million TSS tags in anopheles mosquitoes that transmit malaria, tsetse flies that transmit trypanosomiasis and dust mites that cause allergic dermatitis and bronchial asthma. By providing the largest integrated full-length cDNA data resources in the apicomplexa parasites as well as their vectors, Full-Malaria/Parasites and Full-Arthropods should help combat parasitic diseases. Full-Malaria/Parasites and Full-Arthropods are accessible from http://fullmal.hgc.jp/.
机译:Full-Malaria / Parasites是一个用于蜂复合体和其他寄生虫转录组研究的数据库,该数据库基于我们原始的全长cDNA序列和物理cDNA克隆资源。在此更新中,数据库已扩展为包含幕府将军测序,其中包括来自六个复合体寄生虫和680万个转录起始位点(TSS)的14 818个非冗余全长cDNA克隆的完整序列。通过使用寡核苷酸封端方法和Illumina GA测序仪的新颖方案进行分析。前者应该是表达基因精确注释的最终数据,而后者应该用于超深表达分析。此外,我们已经启动了全节肢动物,这是一种具有医学重要性的节肢动物的全长cDNA数据库。完整节肢动物在传播疟疾的按蚊中包含50343个单程序列,10399个shot弹枪完整序列和2240万个TSS标签,这些蚊子传播疟疾,传播锥虫病的采采蝇和引起过敏性皮炎和支气管哮喘的尘螨。通过在蚜虫寄生虫及其载体中提供最大的整合全长cDNA数据资源,全疟疾/寄生虫和全节肢动物应有助于防治寄生虫病。可从http://fullmal.hgc.jp/访问Full-Malaria / Parasites和Full-节肢动物。

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