Association of Hyperreflective Foci Present in Early Forms of Age-Related Macular Degeneration With Known Age-Related Macular Degeneration Risk Polymorphisms

Altay Lebriz; Scholz Paula; Schick Tina; Felsch Moritz; Hoyng Carel B.; den Hollander Anneke I.; Langmann Thomas; Fauser Sascha

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Association of Hyperreflective Foci Present in Early Forms of Age-Related Macular Degeneration With Known Age-Related Macular Degeneration Risk Polymorphisms

机译：年龄相关性黄斑变性的早期形式中存在的高反射灶与已知的年龄相关性黄斑变性风险多态性的关联

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摘要

PURPOSE. We evaluated the association of hyperreflective foci (HF) observed in early and intermediate age-related macular degeneration (AMD) with known AMD risk alleles.

机译：目的。我们评估了在早期和中期与年龄相关的黄斑变性（AMD）中观察到的高反射灶（HF）与已知的AMD风险等位基因的关联。

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《Investigative ophthalmology & visual science》 |2016年第10期|共6页
作者
Altay Lebriz; Scholz Paula; Schick Tina; Felsch Moritz; Hoyng Carel B.; den Hollander Anneke I.; Langmann Thomas; Fauser Sascha;
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正文语种 eng
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hyperreflective foci; age-related macular degeneration; ARMS2; HTRA1; CFH; APOE; VEGFA; microglia;

机译：高反射灶;年龄相关性黄斑变性;ARMS2;HTRA1;CFH;APOE;VEGFA;小胶质细胞;

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专利

1. Association of Hyperreflective Foci Present in Early Forms of Age-Related Macular Degeneration With Known Age-Related Macular Degeneration Risk Polymorphisms [J] . Lebriz Altay, Paula Scholz, Tina Schick, Investigative ophthalmology & visual science . 2016,第10期

机译：年龄相关性黄斑变性的早期形式中存在的高反射灶与已知的年龄相关性黄斑变性风险多态性的关联
2. Genetic variants in ARMS2/HTRA1 and APOE loci are associated with hyperreflective foci present in early forms of age-related macular degeneration [J] . Ersoy Lebriz, Scholz Paula, Hoyng Carel C. B., Investigative ophthalmology & visual science . 2016,第12期

机译：Arms2 / HTRA1和ApoE基因座中的遗传变体与早期形式的年龄相关性黄斑变性存在的超腐蚀性焦点相关联
3. Association analysis of genetic polymorphisms and expression levels of selected genes involved in extracellular matrix turnover and angiogenesis with the risk of age-related macular degeneration [J] . Oszajca Katarzyna, Szemraj Maciej, Szemraj Janusz, Ophthalmic genetics . 2018,第6期

机译：细胞外基质周转和血管生成遗传多态性和所选基因表达水平的关联分析，具有年龄相关性黄斑变性的风险
4. Automated Age-Related Macular Degeneration and Diabetic Macular Edema Detection on OCT Images using Deep Learning [C] . Sertan Kaymak, Ali Serener IEEE International Conference on Intelligent Computer Communication and Processing . 2018

机译：使用深度学习的自动相关年龄相关性黄斑和糖尿病黄斑水肿检测OCT图像
5. Gene-environment interaction in age-related macular degeneration: Exogenous estrogen, cigarette smoking, and VEGF pathway polymorphisms. [D] . Courtenay, Monique Dorcel. 2014

机译：年龄相关性黄斑变性中的基因-环境相互作用：外源性雌激素，吸烟和VEGF途径多态性。
6. Association between PEDF gene polymorphisms and the risk of age-related macular degeneration [O] . Yuanyuan Li, Deliang Wang 2017

机译：PEDF基因多态性与年龄相关性黄斑变性的风险之间的关联
7. Associations of TLR4 gene polymorphisms with the risk of age-related macular degeneration in a Chinese Han population [O] . Yu Ling, Fei Xiong 2019

机译：TLR4基因多态性与中国汉族人群年龄相关黄斑变性风险的关联

Association of Hyperreflective Foci Present in Early Forms of Age-Related Macular Degeneration With Known Age-Related Macular Degeneration Risk Polymorphisms

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