Steroid Compounds from Sida szechuensis

摘要

A new steroid compound, 2β,3β,14α,20,21,22R,24-heptahydroxycholest-7-en-6-one (1), was isolated from Sida szechuensis. Its structure was determined by spectroscopic analysis, including extensive 1D and 2D-NMR data. Ten previously known compounds were also identified i.e., 3-O-β-D-glucopyranoside-α-ecdysone, loliolide, 3-OP-D-galactopyranoside-β-ecdysone, 3,4,5,6-tefrahydro-3-methyl-β-carboline-5-carboxylic acid, P-ecdysone, polypodine B, α-ecdysone, β-sitosterol, astragalin 6"-O- (4-hydroxycinnamoyl) and pterosterone. The antibacterial assay of the new compound showed that it has inhibitory effect on Escherichia coli with a concentration of 20 mg/mL.