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A New Diphenylethylene from Arundina graminifolia and Its Cytotoxicity

机译:芒草新二苯乙烯及其细胞毒性

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摘要

A now diphenylethylenes, gramniphenol J (1), was isolated from Arundina graminifolia. Its structure was elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Compound 1 was evaluated for its cytotoxicity against five human tumor cell lines and showed cytotoxicity against PC3 and SHSY5Y cells with IC_(50) values of 8.2 and 7.6 μM.
机译:现在从重生的Arundina graminifolia中分离出了一种二苯基乙烯,萘酚J(1)。通过包括广泛的1D和2D-NMR技术在内的光谱方法阐明了其结构。评估化合物1对五种人类肿瘤细胞系的细胞毒性,并显示其对PC3和SHSY5Y细胞的细胞毒性,IC_(50)值为8.2和7.6μM。

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