A Facile One-Pot Synthesis of 2,4,6-Triarylpyridine in DMSO

摘要

A facile, efficient and practical method for the one-pot synthesis of 2,4,6-triarylpyridines starting from acetophenones, aryl aldehydes and ammonium acetate by the use of catalytic amounts of 40 % potassium hydroxide in dimethyl sulfoxide is presented. The present methodology offers attractive features such as the ease of workup, short reaction time and good yields of the products and it does not need any complex catalyst.