Reductive Coupling of Aromatic Aldehydes and Acetophenone Induced by TiCl4-Al/CH2(COOEt)2

摘要

Induced by TiCl4-Al/CH2(COOEt)2 in CH2CI2, some aromatic aldehydes and acetophenone can afford the corresponding 1,2-diols in 13-91 % yields with good dl-diastereoselectivities within 45-60 min at room temperature.