An Efficient and Convenient Procedure for Preparation of 5-Arylidene Barbituric Acid Catalyzed by ZrO2/SO_4~(2-) Solid Superacid with Grinding

摘要

An efficient and convenient approach to the condensation reaction of aromatic aldehydes and barbituric acid using ZrO2/SO_4~(2-) solid superacid as catalyst with grinding at room temperature (without any solvent) is described.This method provides several advantages such as neutral condition,high yields and environment friendly.