In this paper we describe the development of a 5 mm NMR flow tube that can be used in a standard 5 mm NMR probe, enabling the user to conduct experiments on flowing samples or, more specifically, on flowing reaction mixtures. This enables reaction monitoring or kinetic experiments to be conducted by flowing reaction mixtures from a reaction vessel to detection in the coil area of the NMR, without the need for a specialized flow NMR probe. One of the key benefits of this flow tube is that it provides flexibility to be used across a range of available spectrometers of varying magnetic field strengths with a standard 5 mm probe setup. The applicability of this flow tube to reaction monitoring is demonstrated using the reaction of p-phenylenediamine and isobutyraldehyde to form the diimine product.
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机译：在本文中，我们描述了可用于标准5 mm NMR探针的5 mm NMR流量管的开发，使用户能够对流动样品或更具体地对流动的反应混合物进行实验。这使得通过将反应混合物从反应容器中流到NMR线圈区域进行检测，可以进行反应监测或动力学实验，而无需专用的NMR流动探针。这种流量管的主要优点之一是，它具有灵活性，可以在标准磁场5 mm探头设置下，在各种变化磁场强度的可用光谱仪中使用。使用对苯二胺和异丁醛反应生成二亚胺产物证明了该流量管在反应监测中的适用性。
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