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Non-contact Addition, Metering, and Distribution of Liquids into Centrifugal Microfluidic Devices in Motion

机译:非接触式添加,计量和分配液体到运动中的离心微流控设备中

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摘要

A three-dimensional structure was constructed to demonstrate contact-free liquid addition and distribution to a conventional centrifugal microfluidic platform. The structure allowed a continuous stream of liquid to be added to the rotating platform where it was dispensed and metered to a series of reservoirs with 9percent relative standard deviation of the volume. An off-platform generated gradient was used to demonstrate this design's potential to make gradient centrifugal microfluidic chromatography possible without the use of platform space for liquid storage. The system demonstrates a convenient and versatile "World-to-Chip" or more appropriately, World-to-Disk, macro-to-micro interface.
机译:构造了三维结构,以演示无接触液体向常规离心微流控平台的添加和分配。该结构允许将连续的液体流添加到旋转平台上,在该平台上分配液体并将其计量到一系列具有相对体积标准偏差为9%的容器中。使用平台外生成的梯度来证明该设计的潜力,使梯度离心微流色谱法成为可能,而无需使用平台空间来存储液体。该系统演示了方便且通用的“世界到芯片”或更合适的“世界到磁盘”宏到微型接口。

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