Imaging bacterial infections in live mice

摘要

Bradley Smith and colleagues at the University of Notre Dame, Phillip Morris USA, and Washington University School of Medicine have developed a new probe that traces the location of bacteria in the body of a live animal. They chose a NIR fluorophore because signals from dyes with emission wavelengths in the 650-900-nm region can propagate through >2 cm of tissue-a property necessary for imaging in a live animal.