Gel electrophoresis and MEKC join forces on chip

摘要

Gel- and CE-based protein separations have come together at last on a plastic chip.In this issue of Analytical Chemistry (pp 3519-3527),Steven Soper and Hamed Shadpour of Louisiana State University describe a PMMA microflu-idic chip on which proteins are separated in two dimensions by SDS microcap-illary gel electrophoresis (mu CGE)and micellar electrokinetic chromatography (MEKC).With the new chip,a protein mixture can be separated in approx 12 min.