Paper-Based Blood Typing Device That Reports Patient's Blood Type 'in Writing'

摘要

The British author, J. K. Rowling, presented a visionary idea in her novel "Harry Potter and the Chamber of Secrets" that one can interrogate a piece of paper for information and get unambiguous answers from the paper in writing. Here we report a study, following her vision, on using a low-cost bioactive paper device to perform ABO and rhesus (RhD) blood typing tests and obtain test results from the paper in writing. Paper text patterns are designed and printed to allow interactions between grouping antibodies and red blood cells. Composite text patterns consisting of the bioactive and non-bioactive sections are used to form the letters and symbols for the final display of the testing report. This paper-based blood typing device rapidly reports patient's blood type in unambiguous written text.