Rhodium-Catalyzed Cross-Coupling of Organoboron Compounds with Vinyl Acetate

摘要

Transition-metal-catalyzed cross-coupling of organometallics with organohalogen compounds is a powerful approach for connecting two molecules by a carbon-carbon bond. In organic synthesis, either organobromine or organoiodine compounds are typically used as the coupling partners with an organometallic compound. The chloro or sulfonate group is occasionally chosen as the leaving group of the electrophilic substrate. Furthermore, the organometallic compounds can couple with an electrophilic substrate bearing a phosphate, alkoxy, thio, siloxy, diazonium, ammonium, suffonium, chlorosulfonyl, triazene, azole, or phosphonium group.