Induced-Fit Formation of a Tetrameric Organic Capsule Consisting of Hexagram-Shaped Amphiphile Molecules

摘要

Induced-fit molecular recognition is a key event in signal transduction,activation of reaction centers, and allo-steric regulation, and is accompanied by conformational changes around the recognition sites. The general concept that a suitable guest molecule can alter the structure of its host molecule to result in a stable host-guest complex has been widely applied to the selective formation of self-assembled host molecules that are in dynamic equilibrium with a template guest species. Such a system would allow the size-, shape-, and number-dependent inclusion of guest species by host molecules that are formed in a highly adaptive manner from elaborate building blocks under given conditions.