Haemoglobin-C gene in India?

摘要

Mammalian haemoglobin (Hb) molecule is a conjugated protein consisting of four or five different peptide chains. These are designated as alpha (α ), beta (β ), gamma (γ ) and delta (δ ) with an alleged fifth type represented as epsilon (ε). Each chain has intimately but reversibly bound to it a molecule of the iron containing porphyrin ring called haem. Human haemoglobin contains two identical alpha chains; other two chains are either β, γ or δ . The various polypeptide chains, similar in the overall length, differ in the number and type of amino acid residues. The α -chain has 141 residues and β, γ and δ chains have 146 residues each.