Ni-catalyzed reductive allylation of unactivated alkyl halides with allylic carbonates

摘要

Game of two electrophiles: Two partially positively charged sp ~3 carbon atoms can be connected by using a catalytic Ni species in the presence of an environmentally benign Zn reductant, delivering allylated alkanes (see scheme). This unprecedented approach allowed a variety of unactivated alkyl halides and substituted allylic carbonates to regioselectively afford E-alkenes in good to excellent yields.