首页> 外文期刊>Blood: The Journal of the American Society of Hematology >A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

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A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations

机译：冯·威勒布兰德因子A1域前面的短N末端片段通过掩盖2B型VWD突变簇集的区域来阻止A1结合血小板。

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《Blood: The Journal of the American Society of Hematology》 |2016年第22期|共6页
作者
Deng Wei; Wang Yingchun; Lollar Pete; Li Renhao;
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1. A Short N-Terminal Fragment in Front of the A1 Domain of Von Willebrand Factor Prevents the A1 from Binding the Platelet By Masking a Region Clustered By Type 2B VWD Mutations [J] . Deng Wei, Wang Yingchun, Lollar Pete, Blood: The Journal of the American Society of Hematology . 2016,第22期

机译：冯·威勒布兰德因子A1域前面的短N末端片段通过掩盖2B型VWD突变簇集的区域来阻止A1结合血小板。
2. The co-influence of VWD type 2B/2M mutations in the A1 domain and platelet GPIb alpha on the rate of cleavage to VWF by ADAMTS13 [J] . Ma Zhenni, Su Jian, Zhang Jingyu, Thrombosis Research: An International Journal on Vascular Obstruction, Hemorrhage and Hemostasis . 2015,第5期

机译：AAM结构域中的VWD 2B / 2M型突变和血小板GPIbα对ADAMTS13切割VWF的速率的共同影响
3. N-terminal Flanking Region of A1 Domain in von Willebrand Factor Stabilizes Structure of A1A2A3 Complex and Modulates Platelet Activation under Shear Stress [J] . Matthew Auton, Katie Sowa, Molly Behymer, The Journal of biological chemistry . 2012,第18期

机译：A1结构域的N-末端侧翼区域在von Willebrand系数稳定A1A2A3复合物的结构，并在剪切应力下调节血小板活化
4. Dynamics of type IIb mutation-induced conformational changes in the von Willebrand factor A1 domain [C] . H. Shankaran, Y. Zhou, S. Neelamegham Joint Engineering in Medicine and Biology Society-Biomedical Engineering Society Conference . 2002

机译：von Willebrand因子A1域型IIB型突变突变的构象变化的动态
5. Understanding the Regulation of the Shear-Enhanced Binding of the Platelet Protein GPIbalpha and the A1 Domain of von Willebrand Factor. [D] . Penkala, Rebecca A. 2010

机译：了解血小板蛋白GPIbalpha和von Willebrand因子的A1结构域的剪切结合的调节。
6. The N-terminal Flanking Region of the A1 Domain Regulates the Force-dependent Binding of von Willebrand Factor to Platelet Glycoprotein Ibα [O] . Lining Ju, Jing-fei Dong, Miguel A. Cruz, 2013

机译：A1域的N端侧翼区域调节von Willebrand因子与血小板糖蛋白Ibα的力依赖性结合。
7. Identification of two mutations (Arg611Cys and Arg611His) in the A1 loop of von Willebrand factor (vWF) responsible for type 2 von Willebrand disease with decreased platelet-dependent function of vWF see comments [O] . L Hilbert, C Gaucher, C Mazurier 1995

机译：在A1环的鉴定中鉴定A1环路的von Willebrand因子（VWF）负责2型von Willebrand疾病，随着VWF的血小板依赖性函数而减少参阅评论

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