Electroporation of Dicer-Substrate siRNA Duplexes Targeting Endogenous TCR Enhance Tumor Killing Activity of Wilms' Tumor 1 (WT1)-Specific TCR-Redirected Cytotoxic T Cells

Campillo-Davo Diana; Fujiki Fumihiro; Van den Bergh Johan M. J.; Smits Evelien L.; Sugiyama Haruo; Van Tendeloo Viggo F. I.; Berneman Zwi N.

首页> 外文期刊>Blood: The Journal of the American Society of Hematology >Electroporation of Dicer-Substrate siRNA Duplexes Targeting Endogenous TCR Enhance Tumor Killing Activity of Wilms' Tumor 1 (WT1)-Specific TCR-Redirected Cytotoxic T Cells

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Electroporation of Dicer-Substrate siRNA Duplexes Targeting Endogenous TCR Enhance Tumor Killing Activity of Wilms' Tumor 1 (WT1)-Specific TCR-Redirected Cytotoxic T Cells

机译：靶向内源性TCR的Dicer底物siRNA双链体的电穿孔增强了Wilms肿瘤1（WT1）特异性TCR定向细胞毒性T细胞的肿瘤杀伤活性。

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《Blood: The Journal of the American Society of Hematology》 |2016年第22期|共5页
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Campillo-Davo Diana; Fujiki Fumihiro; Van den Bergh Johan M. J.; Smits Evelien L.; Sugiyama Haruo; Van Tendeloo Viggo F. I.; Berneman Zwi N.;
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1. Electroporation of Dicer-Substrate siRNA Duplexes Targeting Endogenous TCR Enhance Tumor Killing Activity of Wilms' Tumor 1 (WT1)-Specific TCR-Redirected Cytotoxic T Cells [J] . Campillo-Davo Diana, Fujiki Fumihiro, Van den Bergh Johan M. J., Blood: The Journal of the American Society of Hematology . 2016,第22期

机译：靶向内源性TCR的Dicer底物siRNA双链体的电穿孔增强了Wilms肿瘤1（WT1）特异性TCR定向细胞毒性T细胞的肿瘤杀伤活性。
2. Chemoimmunotherapy targeting Wilms' tumor 1 (WT1)-specific cytotoxic T lymphocyte and helper T cell responses for patients with pancreatic cancer [J] . Koido Shigeo, Homma Sadamu, Okamoto Masato, Oncoimmunology. . 2014,第10期

机译：针对胰腺癌患者针对Wilms'肿瘤1（WT1）特异性细胞毒性T淋巴细胞和辅助性T细胞反应的化学免疫疗法
3. Gemcitabine enhances Wilms’ tumor gene WT1 expression and sensitizes human pancreatic cancer cells with WT1-specific T-cell-mediated antitumor immune response [J] . Akitaka Takahara, Shigeo Koido, Masaki Ito, Cancer Immunology, Immunotherapy . 2011,第9期

机译：吉西他滨可增强Wilms肿瘤基因WT1的表达，并通过WT1特异性T细胞介导的抗肿瘤免疫应答使人胰腺癌细胞敏感
4. TAP expression level in tumor cells defines the nature and processing of MHC class I peptides for recognition by tumor-specific cytotoxic T lymphocytes [C] . Faten El Hage, Aurélie Durgeau, Fathia Mami-Chouaib Federation of Immunological Societies of Asia-Oceania. . 2013

机译：肿瘤细胞中的敲击表达水平定义了MHC类I肽的性质和加工，用于通过肿瘤特异性细胞毒性T淋巴细胞识别
5. Transcriptional targets of the Wilms' tumor suppressor WT1 and its tumor-associated variants. [D] . Palmer, Rachel Elizabeth. 2003

机译：Wilms肿瘤抑制因子WT1及其肿瘤相关变体的转录靶标。
6. The Antitumor Activity of TCR-Mimic Antibody-Drug Conjugates (TCRm-ADCs) Targeting the Intracellular Wilms Tumor 1 (WT1) Oncoprotein [O] . Ying Shen, Yi-Ming Li, Jing-Jing Zhou, 2019

机译：TCR模拟抗体药物偶联物（TCRm-ADCs）靶向细胞内毒瘤肿瘤1（WT1）癌蛋白的抗肿瘤活性。
7. Chemoimmunotherapy targeting Wilms’ tumor 1 (WT1)-specific cytotoxic T lymphocyte and helper T cell responses for patients with pancreatic cancer [O] . Shigeo Koido, Sadamu Homma, Masato Okamoto, 2014

机译：靶向胰腺炎肿瘤1（WT1）特异性细胞毒性T淋巴细胞和辅助T细胞应对胰腺癌的患者的化疗疗法
8. Enhanced Eradication of Lymphoma by Tumor-Specific Cytotoxic T-Cells Secreting an Engineered Tumor-Specific Immunotoxin [R] . Yotnda, P. 2010

机译：通过肿瘤特异性细胞毒性T细胞分泌工程化肿瘤特异性免疫毒素，增强根除淋巴瘤

Electroporation of Dicer-Substrate siRNA Duplexes Targeting Endogenous TCR Enhance Tumor Killing Activity of Wilms' Tumor 1 (WT1)-Specific TCR-Redirected Cytotoxic T Cells

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