New Plant Expression Systems Drive Vaccine Innovation and Opportunity

摘要

plant expression systems are emerging as fast and inexpensive methods for producing vaccines. Someday, plants may surpass mammalian and even many microbial systems in efficiency and cost-benefits for the manufacture recombinant proteins. This is particularly so for the rapid manufacture of truly large-scale (million- or even billion-dose) vaccine antigens. Whether grown as single cells or tissues in photosynthesis reactors, as whole plants in controlled laboratory situations, or cultivated in fieldsof transformed food-commodity plants (e.g., rice, potatoes, or tobacco), plants being adapted for recombinant protein manufacture offer high yields and relatively low investment costs. These systems can move quickly from identification of a candidate toexpression, testing, and manufacture.