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Current outbreak of Staphylococcus aureus

机译:当前金黄色葡萄球菌的暴发

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摘要

Staphylococcus aureus has long been recognized as one of the major human pathogens and is responsible for a wide range of diseases, from superficial skin infections to life-threatening infections. The position of S. aureus as one of the most important opportunistic human pathogens is largely attributable to the combination of its virulence potential and its ubiquitous occurrence as a colonizer in humans, domestic animals, and livestock. Molecular typing allows several important observations to be made regarding the evolution, epidemiology and spread of S. aureus clones with particular public health importance [I]. It appears that, over wide geographical regions, certain clones have emerged, disseminated, and sometimes disappeared. It is speculated that clone histories could result from the balance between occasional acquisition or loss of virulence and/or antimicrobial resistance determinants and selective pressure.
机译:长期以来,金黄色葡萄球菌一直被认为是人类主要病原体之一,并引起从浅表皮肤感染到危及生命的各种疾病。金黄色葡萄球菌作为最重要的机会性人类病原体之一的地位在很大程度上归因于它的毒力潜力和在人类,家畜和牲畜中作为定居者的普遍存在。分子分型使人们对金黄色葡萄球菌克隆的进化,流行病学和传播具有重要的观察意义,具有特别的公共卫生意义[I]。看起来,在广阔的地理区域中,某些克隆已经出现,传播并有时消失。据推测,克隆历史可能是由于偶尔获得或丧失毒力和/或抗微生物药耐药性决定因素与选择压力之间的平衡而引起的。

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