Acinetobacter baumannii respiratory isolates in ventilated patients are associated with prolonged hospital stay.

摘要

We read with interest the excellent review in CMI concerning the clinical impact and pathogenicityof Acinetobacter, and wish to contribute our own observations from Malaysia. In a retrospective review of 404 cases of mechanically-ventilated patients in our urban-based, 800-bed, university teaching hospital in Malaysia between 2003 and 2004, 102 (25.2%) patients yielded negative cultures, and Acinetobacter baumannii ranked highest among all positive respiratory isolates, accounting for 141 (46.7%) of all patients yielding positive cultures. Only 16.7% of A. baumannii isolates showed susceptibility to all major potent antibiotic classes (extended-spectrum beta-lactams, fourth-generation cephalosporins,carbapenems and aminoglycosides), while 68.1% of isolates showed multiresistance.