Cyanosis involving the hands and toes of a 12-year-old girl was first noted 3 months before medical evaluation was sought. Her fingers and palms were red, the nail beds were cya-notic, and her palms were cold and sweaty. The girl's toes were cyanotic when she was standing. Her hands and feet reverted to a normal color when the limbs were elevated. The remainder of the physical examination was normal. This presentation is typical of acrocyanosis-a benign condition that is most common in teenaged girls.1 Localization to the extremities and no involvement of the lips can help differentiate acrocyanosis from more serious forms of cyanosis. The persistent rather than in-
展开▼
