Realization of highly localized exposure of small animal by absorbing material attached holder

摘要

In testing possible biological effects of electromagnetic exposure from cellular telephones of small animals such as mice, it is essential to realize a highly localized bead exposure in the mouse as close as possible to that of a cellular telephone exposure actually occurring in a human. In this study, a prototype exposure setup was developed with a highly localized specific absorption rate (SAR) in the mouse brain and a low whole-body averaged SAR. The low whole-body averaged SAR was realized by using a flexible magnetic sheet attachment to the mouse holder. Its validity has carefully been examined by both numerical simulation with an anatomically based mouse model and experimental simulation with a solid mouse phantom. Good agreement has been obtained between the numerical and experimental results, which confirmed the effectiveness of the magnetic sheet attachment to the mouse holder.