NIR Spectroscopy Analysis of Phosphate Salts: Qualitative Identification and Quantitative Contamination

摘要

Conflrmation of raw material quality is a vital part of biopharmaceutical manufacturing processing. Incorrect or poor-quality vendor materials account for a considerable portion of failed and recalled product. To prevent these expensive problems, strict quality control (QC) procedures are often implemented and used to screen for inappropriate incoming materials. QC procedures commonly used are chemical tests that involve removing samples to a laboratory and performing, which can at times be complex,time-consuming, and laborious protocols. A common test procedure that is considerably easier and quicker to perform than laboratory chemical tests involves near-infrared (NIR) spectroscopy.