A NEW E-RING γ-LACTONE PENTACYCLIC TRITERPENE FROM Lysimachia clethroides AND ITS CYTOTOXIC ACTIVITIES

摘要

A new E-ring γ-lactone pentacyclic triterpene, 3β-myristoxyurs-12-en-19,28-olide, has been isolated from the chloroform extract of Lysimachia clethroides Duby, together with four known pentacyclic triterpenoid acids. The structures of the compounds were elucidated by comprehensive spectroscopic analyses. All of the compounds showed various degrees of cytotoxic activities in MTT assay.