A NEW CERAMIDE FROM THE ROOT OF Isatis indigotica AND ITS CYTOTOXIC ACTIVITY

摘要

In addition to two ceramides 1-O-β-D-glucopyranosyl-(2S,3R)-N-(2'-hydroxyhexadecanoyl)-octadeca-4E,8E-sphingenine (2) and (2S,3S,4R)-N-(2'-hydroxytetracosanoyl)-octadecasphingenine (3), which separated for the first time, a new ceramide 1-O-β-D-glucopyranosyl-(2S,3R)-N-(2'-hydroxyhexacosanoyl)-octadecasphingenine (1) was isolated from the traditional Chinese medicinal herb Isatis indigotica. Their cytotoxic effects were evaluated by the MTT method.