首页> 外文期刊>Basic Research in Cardiology: Official Journal of the German Association of Cardiovascular Research >Erratum: Conditional transgenic expression of TIR-domain-containing adaptor-inducing interferon-β (TRIF) in the adult mouse heart is protective in acute viral myocarditis (Basic Research in Cardiology DOI: 10.1007/s00395-011-0226-4)
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Erratum: Conditional transgenic expression of TIR-domain-containing adaptor-inducing interferon-β (TRIF) in the adult mouse heart is protective in acute viral myocarditis (Basic Research in Cardiology DOI: 10.1007/s00395-011-0226-4)

机译:勘误:成年小鼠心脏中含有TIR结构域的衔接子诱导干扰素-β(TRIF)的条件转基因表达在急性病毒性心肌炎中具有保护作用(心脏病学基础研究DOI:10.1007 / s00395-011-0226-4)

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This article contains statements suggesting that EMCV belongs to the genus Enterovirus. While both EMCV and CVB3 belong to the Picornaviridae family, EMCV belongs to the genus Cardiovirus and CVB3 to the genus Enterovirus. The correct statements are listed below:(1) Accordingly, in this study, we demonstrated that cardiac-specific overexpression of TRIF led to the upregulation of antiviral molecules that are essential for efficient defense against EMCV-induced myocarditis and myocardial dysfunction.(2) Two recent studies have shown that MDA5 is critical for detection of picornaviruses [9, 15].The authors apologize for any confusion this may have created.
机译:本文包含的建议表明EMCV属于肠病毒属。虽然EMCV和CVB3都属于Picornaviridae家族,但EMCV属于心脏病毒属,而CVB3属于肠病毒属。正确的陈述如下:(1)因此,在这项研究中,我们证明了TRIF的心脏特异性表达导致抗病毒分子上调,这对于有效防御EMCV诱发的心肌炎和心肌功能障碍至关重要。(2)最近的两项研究表明,MDA5对于检测小核糖核酸病毒至关重要[9,15]。作者对此可能造成的困惑深表歉意。

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