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Use of herbal preparations in the treatment of oxidant-mediated inflammatory disorders

机译:草药制剂在治疗氧化剂介导的炎症中的用途

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摘要

Complementary and alternative medicine (CAM) use has increased in popularity in recent years and herbal therapy alone is now a billion dollar market. For centuries herbs have been used as food and for medicinal purposes. Various herbs have been identified as possessing anti-inflammatory and antioxidative properties, and they are currently being used to treat inflammatory disorders as well as those caused by reactive oxygen species (ROS). Asthma Alzheimer's disease, inflammatory bowel disease (IBD), rheumatoid arthritis (RA), and atherogenesis are all disorders where inflammation and ROS are involved in their pathogenesis. This review examines the pathogenesis of the above mentioned ROS-mediated inflammatory disorders, as well as discusses the antioxidant and anti-inflammatory mechanisms of various herbs and the clinical trials where herbs have been used to treat these disorders.
机译:近年来,补充和替代医学(CAM)的使用已日益普及,仅草药疗法就已成为十亿美元的市场。几个世纪以来,草药一直被用作食品和药用目的。已经鉴定出各种具有抗炎和抗氧化特性的草药,它们目前被用于治疗炎症性疾病以及由活性氧(ROS)引起的疾病。哮喘,阿尔茨海默氏病,炎性肠病(IBD),类风湿关节炎(RA)和动脉粥样硬化均是炎症和ROS参与其发病机理的所有疾病。这篇综述检查了上述ROS介导的炎性疾病的发病机理,并讨论了各种草药的抗氧化剂和抗炎机制以及其中草药已用于治疗这些疾病的临床试验。

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