Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sensitivity of the chemotherapy drug CPT-11

Xie Fang-Wei; Peng Yong-Hai; Wang Wen-Wu; Chen Xi; Chen Xiong; Li Jie; Yu Zong-Yang; Ouyang Xue-Nong

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Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sensitivity of the chemotherapy drug CPT-11

机译：大肠癌细胞中UGT1A1基因甲基化水平对化疗药物CPT-11敏感性的影响

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摘要

Objective: To study the influence of the methylation level of UGT1A1 gene related to CPT-11 metabolic enzymes in colorectal cancer cells on the sensitivity of chemotherapy drugs.

机译：目的：研究大肠癌细胞中与CPT-11代谢酶相关的UGT1A1基因甲基化水平对化疗药物敏感性的影响。

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来源
《Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie》 |2014年第7期|共7页
作者
Xie Fang-Wei; Peng Yong-Hai; Wang Wen-Wu; Chen Xi; Chen Xiong; Li Jie; Yu Zong-Yang; Ouyang Xue-Nong;
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正文语种 eng
中图分类治疗学;
关键词
UGT1A1 gene; Methylation; CPT-11; Chemotherapy resistance; Colorectal cancer;

机译：UGT1A1基因甲基化CPT-11化疗耐药大肠癌;

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1. Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sensitivity of the chemotherapy drug CPT-11 [J] . Xie Fang-Wei, Peng Yong-Hai, Wang Wen-Wu, Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2014,第7期

机译：大肠癌细胞中UGT1A1基因甲基化水平对化疗药物CPT-11敏感性的影响
2. Sensitivity of Cells with Various Levels of Ppmld Expression to Classical Chemotherapeutic Drugs for Colorectal Cancer Treatment [J] . E. Yu. Kochetkova, B. B. Grigorash, O. N. Demidov Cell and Tissue Biology . 2019,第5期

机译：具有各种水平PPMLD表达对古典化学治疗药物的细胞敏感性，用于结直肠癌治疗
3. The research on the influences of hyperthermal perfusion chemotherapy combined with immunologic therapy on the immunologic function and levels of circulating tumor cells of the advanced colorectal cancer patients with liver metastasis [J] . J.-J. Sun, G.-L. Fan, X.-G. Wang, European review for medical and pharmacological sciences. . 2017,第13期

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4. Combined photothermo-chemotherapy using gold nanoshells on drug- loaded micelles for colorectal cancer treatment [C] . Shin-Yu Lee, Ming-Jium Shieh Colloidal nanoparticles for biomedical applications XIII . 2018

机译：在载药胶束上使用金纳米壳的光热化学疗法联合治疗大肠癌
5. Therapeutic Targeting of Chemotherapy-Resistant Colorectal Cancer Stem Cells with P73- and Trail-Based Small Molecules [D] . Prabhu, Varun Vijay. 2016

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6. Induced pluripotent stem cell-related genes influence biological behavior and 5-fluorouracil sensitivity of colorectal cancer cells [O] . Zhong Shi, Rui Bai, Zhi-xuan Fu, 2012

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7. Correlation between the promoter methylation status of ATP-binding cassette sub-family G member 2 and drug sensitivity in colorectal cancer cell lines [O] . HYUN-HYE MOON, SUNG-HEE KIM, JA-LOK KU 2015

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Influence of UGT1A1 gene methylation level in colorectal cancer cells on the sensitivity of the chemotherapy drug CPT-11

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