Changing electrophysiological parameters in the eye in children with insulin-dependent diabetes mellitus

摘要

Fifty-eight (58) children with insulin-dependent diabetes mellitus (IDDM) were examined and shared between 6 groups: Group 1--primarily diagnosed diabetes mellitus (DM); Group 2--DM with an up to 5-year history; Group 3--DM with a an up to 10-year history; Group 4--children with non-proliferative diabetic retinopathy; Group 5--children with diabetic cataract. Forty-five healthy children were in the control group. According to the pattern registration of visual induced potentials (RVIP), a reliable prolongation of latency P100 was detected in children of Groups 1 and 4. The results of the general electroretinography (ERG) showed a reliably decreased amplitude of the basic wave b- in Groups 1-4 and an increased amplitude of wave a- in Groups 4 and 5. According to photopic ERG, a reliably decreased amplitude of wave a- was detected in Groups 1-5 and a decreased amplitude of wave b- was registered in all groups except for Group 2. Scotopic ERG showed, in Group 5, an increased amplitude of wave a- (p < 0.05) at the normal values of wave b-, and, in Groups 1-4,--a significantly inhibited amplitude of wave b-. Finally, rhythmic ERG showed a reliably inhibited amplitude in all groups.