A comparative evaluation of the oxidant and antioxidant blood systems in rabbits with caustic burns of the eyes in their treatment by synthetic and natural antioxidants

摘要

A method of provoking a caustic burn was described on the basis of experiments made in 36 rabbits (72 eyes) who were shared between 2 groups. Effects from histochrom, a natural antioxidant, and from emoxipin, a synthetic antioxidant, produced on the lipid-peroxidation parameters at early stages of ocular burn disease were studied. A higher clinical efficiency of histochrom versus emoxipin was demonstrated.