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首页> 外文期刊>Computers in Biology and Medicine >Linked metabolites: a tool for the construction of directed metabolic graphs.
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Linked metabolites: a tool for the construction of directed metabolic graphs.

机译:关联代谢物:用于构建有向代谢图的工具。

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摘要

Metabolic pathway diagrams provide a wealth of information on how reactions combine to perform biological functions. While pathway diagrams are arranged in a way that allows a specific area of metabolism to be visualised, the inherent complexity of each pathway makes it difficult to identify the sets of reactions linking groups of compounds; a common task for researchers attempting to explain observed correlations or looking for further compounds of potential interest to use in validation work. Here we introduce Linked Metabolites, a tool that identifies sets of reactions linking groups of compounds in the context of the KEGG pathway diagrams.
机译:代谢途径图提供了大量有关反应如何结合以执行生物学功能的信息。尽管路径图的排列方式可以使特定的代谢区域可视化,但每种路径的内在复杂性使得很难确定连接化合物组的反应集。对于研究人员来说,这是一项常见的任务,他们试图解释观察到的相关性或寻找在验证工作中可能使用的其他潜在化合物。在这里,我们介绍链接的代谢物,该工具可识别在KEGG途径图中关联化合物组的反应集。

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