Intravenous anesthesia using continuous administration of propofol and fentanyl: fentanyl administration procedure and quality of awareness

摘要

BACKGROUND: We studied total intravenous anesthesia using continuous administration of propofol and fentanyl and examined especially the method of fetanyl administration. METHODS: Anesthesia was induced with fentanyl 2 micrograms.kg-1 and propofol 2 mg.kg-1. Fentanyl 1 microgram.kg-1 was then administered before the start of the operation and infused continuously at a rate of 0.02 microgram.kg-1.min-1 during operation. Propofol was also infused continuously at 4-10 mg.kg-1.min-1. RESULTS: These methods allowed a significant reduction in the necessary dose of fentanyl and propofol compared with ordinary methods, and a stable general condition was maintained during the operation. Additionally, high quality of awareness was obtained after the recovery. CONCLUSIONS: This continuous administration procedure of fentanyl reduced the total doses of both propofol and fentanyl, allowing high quality of awareness after the recovery.