Multiscale modelling of fluid flow in charged porous media including cationic exchanges: application to bone tissues

摘要

Multiscale modelling of fluid How in charged porous media including cationic exchanges: application to bone tissues. To better understand the bone diseases, many models of porous cortical bone have been developed to simulate its in vivo behaviour. Thus we proposed multiscale models including multiphysical phenomena governing the hydraulic response of bone. However, all these models neglected the possible ionic exchanges at the cellular level. Since such chemical reactions directly change the physico-chemical properties of the tissue, the interstitial flow is also modified. The aim of this study is so to include these ionic exchanges in the bone fluid transport description by deriving their consequences at the macroscale. To cite this article: J. Kaiser et al., C. R. Mecanique 337 (2009).