Analysis of slow motions in the micro-millisecond range on domain 1 of annexin I

摘要

A preliminary study of the dynamics of the domain 1 of annexin I by Nuclear Magnetic Resonance is presented.The use of ~15N-relaxation-compensated CPMG experiments allowed us to show the presence of conformational motions in the micro-millisecond range that extend over several segments along the domain.For 14 residues,exchange rate constants could be evaluated,and were found in the range 1300-2500 s~(-1).To cite this article:M.Gallopin et al,C.R.Chimie 00(2004).