Nano titania-supported sulfonic acid catalyzed synthesis of alpha,alpha '-bis(substituted-benzylidene)cycloalkanones and of their xanthene derivatives under solvent-free conditions

摘要

An efficient, rapid and green synthesis of alpha,alpha'-bis(substituted-benzylidene)cycloalkanones and their xanthene derivatives is reported under solvent-free conditions using nano titania-supported sulfonic acid (n-TSA) as a reusable catalyst. This method offers many advantages, such as environmental friendliness reaction conditions, simplicity, short reaction times, easy work-up, reusability of catalyst, and high yields of products. Eight new compounds are reported too. (c) 2014 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.