Deuteration of the chitin-glucan complex in the mycelium of Aspergillus niger

摘要

Biosynthesis in heavy water was used to achieve deuteration of the chitin-glucan complex in the mycelium of Aspergillus niger. The biosynthesis in heavy water was demonstrated to be less active compared to that taking place under ordinary conditions. Chemical composition of the complex and its supramolecular organization were studied. NMR-H~1 demonstrated that deuteration occurs at position C-2 of the N-acetylglucosamine pyranose ring of the chitin macrochain.