Synthesis and characterization of novel dipeptide mimetics with hydantoin moiety

摘要

The synthesis of three novel 5,5-dimethylhydantoin derivatives 2-amino-N-(4,4-dimethyl-2,5-dioxoimidazolidin-l-yl)aeetamide, 2-amino-N-(4,4-dimethyl-2,5-dioxoi-midazol idin-1-yl)-3-phenylpropanamide, and 2-amino-4-methyl-N-(4,4-dimethyl-2,5-dioxoimidazol idin-1-yl) pentanamide, is reported. The newly synthesized compounds have been characterized by infrared (IR), MS, and NMR (~1H and ~(13)C) spectra.