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Vaccines of the Future: The Role of Inflammation and Adjuvanticity

机译:未来的疫苗:炎症和佐剂的作用

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摘要

With the increase of life expectancy worldwide, people expect a better quality of life, and vaccination is possibly one of the best tools for improving it. In addition to developing or improving vaccines for the elimination of infectious diseases such as malaria, tuberculosis and AIDS, the challenge of future vaccination strategies is both to improve efficacy of currently available vaccines for groups of people with frail immunity, such as the elderly or patients with chronic diseases, and to develop new vaccines for non-communicable diseases such as autoimmunity and cancer. More personalized or precise vaccination is one of the aims of future vaccines, taking into account age, gender, health and nutritional status, together with geographical/environmental conditions.
机译:随着全球预期寿命的增加,人们期望生活质量得到改善,而疫苗接种可能是改善生活质量的最佳工具之一。除了开发或改进用于消除疟疾,结核病和艾滋病等传染病的疫苗外,未来的疫苗接种策略所面临的挑战还在于提高针对弱免疫人群(例如老年人或患者)的现有疫苗的有效性与慢性疾病有关,并开发针对非传染性疾病(例如自身免疫和癌症)的新疫苗。考虑到年龄,性别,健康和营养状况以及地理/环境条件,更加个性化或精确的疫苗接种是未来疫苗的目标之一。

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