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首页> 外文期刊>Clinica chimica acta: International journal of clinical chemistry and applied molecular biology >Quantitative assessment of human serum transferrin receptor in breast cancer patients pre- and post-chemotherapy using peptide immunoaffinity enrichment coupled with targeted proteomics
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Quantitative assessment of human serum transferrin receptor in breast cancer patients pre- and post-chemotherapy using peptide immunoaffinity enrichment coupled with targeted proteomics

机译:肽免疫亲和富集结合靶向蛋白质组学对乳腺癌患者化疗前后人血清转铁蛋白受体的定量评估

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摘要

Background: sTfR, a soluble form of transferrin receptor in serum, has been suggested as an indicator of bone marrow failure in breast cancer patients receiving chemotherapy. However, intensive chemotherapy could also cause a reduction of sTfR to a level below the LOQ of most assays.
机译:背景:sTfR是血清中转铁蛋白受体的一种可溶形式,已被建议作为接受化疗的乳腺癌患者骨髓衰竭的指标。但是,强化化疗也可能导致sTfR降低至大多数测定法的最低检测限以下。

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