Effect of Particle Size,Composition,and Thermal Treatment on the Crystalline Structure of Polycaprolactone Nanoparticles

摘要

Biodegradable,biocompatible nanoparticles have been used in various fields,such as drug delivery systems,cosmetics,and tissue engineering.For such applications,these nanoparticles are usually loaded with water-insoluble drugs.Thus,it is imperative that the internal structure of the nanoparticles is known,since specific drug amounts loaded into the nanoparticles and particular drug release patterns are not only dependent on the hydrophilicity of the drug but also on the internal structure of the nanoparticles.