Intracytoplasmic sperm injection allows normal pregnancy rates for males ≥ 40 with low hypoosmotic swelling test scores even when complicated by very low motility percentage

摘要

Purpose: To determine if the additional burden of low percentage motility reduces the chance that sperm with low hypoosmotic swelling (HOS) test scores will achieve a pregnancy following in vitro fertilization (IVF) with intracytoplasmic sperm injections (ICSI). Methods: Couples undergoing IVF-embryo transfer (ET) and ICSI for low HOS tests (< 50%) were retrospectively identified. The percentage motility was divided into deciles. Pregnancy rates were determined according to the deciles of motility. Results: No differences in clinical or live delivered pregnancy rates per transfer were found in even the very lowest percent motility category. Conclusions: The added complicating factor of low percentage motility added to sperm with low HOS test scores does not reduce the effectiveness of IVF with ICSI.