Purpose: Spontaneous retinal venous pulsations (SRVP) arise from an interaction between intraocular pressure (lOP), retinal venous pressure (RVP) and intracranial pressure (ICP). With elevated ICR raised RVP or reduced lOP, the gradient over the intra - extra ocular space decreases leading to cessation of SRVP. Reduced SRVPs have been reported in glaucoma. In this study we examined the amplitude of SRVP and its relationship with lOP in retinal veins near the optic disc. Methods: The study included 10 healthy subjects (mean age: 35 + 10) with no history of eye disease, no head injury, and a normal fundus on ophthalmoscopy with no signs of raised ICP or vascular changes. Baseline lOP was measured (Goldman) and SRVP was recorded using the dynamic retinal vessel analyser (Imedos). The lOP was lowered using a drop of lopi-dine 0.5% and was measured every 15 minutes, followed by a dynamic recording of SPRV for 100 seconds - inferotemporal vein IDD from optic disc. Mean SPRV was determined for a 20 second period of stable recording within each sample at the same site along the vein. The blood pressure and heart rate was tracked continuously throughout (Finipress). RVP was assumed to be constant during the test.
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