Morphological changes in testicular tissue in clean-up personnel after the Chernobyl nuclear reactor accident

摘要

Pathomorphological alterations of testicular tissue were absent in men exposed to total body ionizing radiation in the dose of 1 to 10 cGy. Some changes in seminiferous tubules appeared in the dose of 10 to 20 cGy. Lymphoid infiltration of the seminiferous tubules arose 5 years after the accident and of the interstitial tissue--10-15 years after the radiation in exposure in the dose 20-30 cGy. Autoimmune orchitis affects spermatogenesis early after irradiation. Lymphoid infiltration of the seminiferous tubules and interstitial tissue is observed 5 years after radiation in the dose 30 to 50 cGy. Sclerosis of 50% seminiferous tubules, foci of regeneration of Leydig cells with lymphoid infiltration and interstitial fibrosis takes place 10-15 years after irradiation.