Morphological and immunohistochemical characteristics of blastic NK-cell lymphoma

摘要

This is a review characterizing a rare skin tumor which in the WHO-EORTC classification of skin lymphoma is called CD4+/CD5+ hematodermal tumor (blastic NK-cellular lymphoma). Analysis of clinical picture and results of histological investigation of tumor nodules in the skin and bone marrow does not allow one to reveal specific signs sufficient for diagnosis. Immunohistochemical study with panel of markers including CD4, CD56, CD68, TdT is necessary for this tumor diagnosis.