Angiogenetic features in liver carcinoma and their prognostic value: clinical and immunohistochemical study

摘要

Survival rates were studied in 57 patients with primary liver carcinoma (including 32 with hepatocellular carcinoma [HCC] and 25 with cholangiocellular carcinoma [CCC] in relation to the histological type of a tumor and its microcirculatory bed. In all the patients, tumor resection was performed, followed by chemoemlolization of the liver. The development of tumor microvessels was assessed by the sum of their perimeters. If the size of a vessel was higher than its median, overall survival was 19.3 months, if the size was lower, it was increased by an average of 86.7 months. In patients with CCC, survival did not depend on tumor angiogenesis and it averaged 19.7 months.