Pregnancy rates per embryo transfer (ET) may be improved by conventional oocyte insemination for male factor rather than intracytoplasmic sperm injection (ICSI).

摘要

PURPOSE: To determine if intracytoplasmic sperm injection (ICSI) for mild male factor may create embryos less likely to implant. METHOD: A retrospective analysis of pregnancy outcome following oocyte fertilization with ICSI vs conventional egg insemination was performed. RESULTS: Though there were many less cases using conventional oocyte insemination compared to ICSI so that a meaningful comparison of outcome could not be made, the data could suggest the fertilization by ICSI might result in embryos less likely to implant. CONCLUSIONS: This pilot study should encourage IVF centers to consider conventional oocyte insemination for mild male factor instead of ICSI. Only by evaluating a larger series can it be determined with certainty that fertilization by ICSI may lower the implantation potential of the embryo that is formed.